After being conducted over a 12-week time period with porous cylindrical implants (6 mm x 25 mm), this temporal study displayed RAPID BONE INGROWTH within 2 WEEKS, and FULL THROUGH-GROWTH at 6 WEEKS.
Short-Term Cortical Bone Ingrowth Sheep Study
At 2 Weeks
HISTOLOGY
Demonstrated an intimate bone-to-implant interface. New bone formed directly on the surface of the material and into the pores.
Demonstrated an increase in new bone integration into the porous structures of the implants compared to the 2-week time point.
At 4 Weeks
HISTOLOGY
At 6 Weeks
HISTOLOGY
Demonstrated complete new bone integration throughout the entire porous structure of the implants. Bone ingrowth from one cortex to the other in medial and lateral sites was noted.
Comprehensive bone ingrowth and intimate boney contact throughout the pores in both medial and lateral sites. Interestingly, new bone was seen growing up the implants into the medullary canal.
At 8 Weeks
HISTOLOGY
At 12 Weeks
HISTOLOGY
As noted at 8 weeks, there were areas of osseointegration into the pores of the implant within the medullary canal. Bone appeared to walk through all implants. This supports the impressive osteoconductive properties of Phusion Metal®.
At 4 Months
Lumbar Interbody Fusion Sheep Study
At 4 months, this study demonstrates substantial BONE GROWTH THROUGHOUT THE PORES. Phusion Metal® implants facilitated SUPERIOR BIOMECHANICAL STABILITY and BONE-TO-IMPLANT CONTACT verses PEEK.
PEEK L4/L5
Fibrous connective tissue and fibrocartilaginous tissue completely surround the non-porous cage
PHUSION METAL L4/L5
Complete fusion between the endplates; bone ingrowth throughout the interconnected pores if the fully porous cage
CORONAL & SAGITTAL CT SCANS
Demonstrates solid fusion though the central cavity
